Focus Areas:

• Next-generation immunotherapies and immunomodulatory drugs.
• Manipulation of the tumour microenvironment.
• Novel therapeutics tailored for paediatric cancers.
• Clinical decision support tools for treatment optimisation in children and young people.

Funding Type: Grant

Project Size: Total costs between £150,000 and £4 million, with a maximum grant request of £2 million.

Proposal Criteria:

• Projects should be innovation-driven, focusing on advanced immunotherapies or paediatric cancer treatments.
• Must adhere to the highest standards of animal welfare for proposals involving animal testing.
• Activities can range from laboratory experiments to phase 1 and 2 clinical trials, including prototyping, IP protection, and regulatory planning.

Portfolio Approach:

• Funding a diverse array of projects across immuno-oncology and paediatric oncology themes, technological maturities, and UK geographical locations.

Specific Themes:

• Focus on advanced immunotherapies, tumour microenvironment manipulation, paediatric cancer therapeutics, and clinical dosing optimisation tools.

Research Categories:

• Industrial research and experimental development projects.

Exclusions:

• Therapeutic approaches for adult cancers outside of immuno-oncology scope.
• Cancer diagnostics not aligned with specific immunotherapeutics or paediatric oncology approaches.
• Projects contingent on export performance or domestic input usage.

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