For an increasing number of cancer indications potential mechanisms and means to prevent the onset of cancer have been identified. However, with cancer incidence steadily increasing across all age groups, parts of society, European Member States, Associated Countries and elsewhere, decisive action on primary prevention should be stepped up and made a collective responsibility. Implementing and upscaling of primary cancer-centred prevention programmes would contribute to achieving this goal.
Adoption and efficacy of primary cancer prevention programmes in real-life has been insufficient, due to factors related to local context, such as organisation and digitalisation of healthcare services, resources, cultural, and geographical situation. To appropriately adapt interventions and scale-up to different geographical, economic and cultural settings, proposals should aim at delivering results through implementation research, which are directed, tailored towards and contributing to all of the following expected outcomes:
Investments are needed to establish, scale-up or improve primary cancer prevention programmes. The barriers that prevent their uptake and effective implementation should be identified and addressed. Also, primary cancer prevention programmes should be tailored to the particular needs of the target populations, taking into account socio-economic, cultural and geographical conditions. Digital tools and datasets may be considered where needed.
Proposals should address all of the following:
Clinical trials and translational research are not within the scope of this topic.
This topic requires the effective contribution of social sciences and humanities (SSH) disciplines and the involvement of SSH experts, institutions as well as the inclusion of relevant SSH expertise, in order to produce meaningful and significant effects enhancing the societal impact of the related research activities.
Applicants should demonstrate awareness of relevant projects on implementation research in primary cancer prevention. Successful applicants will be asked to liaise with these different initiatives where applicable, with the Commission acting as a facilitator. Where applicable, funded actions should make use of resources made available by the Knowledge Centre on Cancer.
Furthermore, all projects funded under this topic are strongly encouraged to participate in networking and joint activities with other ongoing projects under the mission on cancer and other cancer relevant projects, as appropriate. These networking and joint activities could, for example, involve the participation in joint workshops, the exchange of knowledge, the development and adoption of best practices, or joint communication activities. This could also involve networking and joint activities with projects funded under other clusters and pillars of Horizon Europe, or other EU programmes, as appropriate.