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Engineering Biology Access to Infrastructure Pilot

Opens:
07.09.2026
Closes:
21.10.2026
Sectors:
Biotechnology
Health & Life Sciences
Agriculture
Project Size:
Between £200,000 to £750,000

Innovate UK has launched the Engineering Biology Access to Infrastructure Pilot, with up to £5 million available to support UK SMEs that are ready to move engineering biology innovations beyond laboratory scale.

The programme is designed to address one of the major challenges facing engineering biology companies: gaining affordable access to the specialist infrastructure and expertise needed to validate whether a technology can operate successfully at pilot or demonstration scale.

Projects must therefore involve a UK organisation with the facilities or capabilities required to support engineering biology scale-up and validation. Pasted text

Key Dates and Funding

Opens: 7 September 2026

Closes: 21 October 2026, 11:00am

Total competition funding: Up to £5 million

Project size: £200,000 to £750,000

Project duration: Up to 24 months

Who Can Apply?

The lead applicant must be a UK registered micro, small or medium-sized enterprise.

Academic institutions cannot lead or apply alone.

The project must also include, either as a partner or subcontractor, a UK registered organisation with the infrastructure and capabilities required to support engineering biology scale-up and validation. This could include a business, academic institution, charity, not-for-profit organisation, public sector organisation or research and technology organisation. Pasted text

What Types of Projects Are in Scope?

Projects must focus on scaling an engineering biology innovation that has already demonstrated robustness at laboratory scale.

The core innovation must arise from the purposeful engineering of biological systems, such as engineered organisms, cells, enzymes, proteins or other biomolecular systems with new or enhanced functions.

Relevant technology areas can include:

  • Biosensors and diagnostics
  • Biomanufacturing systems
  • Biocatalysis and chemical production
  • Engineered biomaterials
  • Metabolic engineering
  • Nucleotide synthesis
  • Engineered proteins and enzymes
  • Cell and microbe engineering
  • Synthetic biology platforms
  • Gene editing and genome engineering
  • AI and computational biology

The project should predominantly focus on scale-up, but supporting activities such as validation, manufacturing development and regulatory progression can also be included where they directly support the underlying engineering biology innovation.

Priority Themes

Projects must align with one or more of the following themes:

  • Health
  • Agriculture and Food
  • Chemicals and materials
  • Low Carbon fuels
  • Waste and environment
  • Cross-cutting technology and service development Pasted text (2)

What Must the Project Demonstrate?

A strong application will need to show that the engineering biology innovation is genuinely ready to move beyond laboratory scale.

Applicants are expected to demonstrate:

  • Evidence that the innovation is robust at lab scale
  • A clear need for pilot or demonstration-scale infrastructure
  • Technical and commercial validation activities
  • A credible route towards industrial-scale application
  • How the project could support future growth of the SME in the UK
  • Access to the facilities, expertise and equipment needed to deliver the scale-up
  • Commercial potential and a clear route to market

Projects may also include activities such as a techno-economic assessment to demonstrate whether the scaled process is commercially viable.


Why This Opportunity Matters

Many engineering biology technologies demonstrate strong performance in laboratory conditions but face substantial technical and commercial challenges when scaled.

Processes that work successfully at small scale may encounter issues with yield, reproducibility, cost, process control, manufacturing compatibility or regulatory requirements when moved towards industrial production.

This programme is intended to help companies address that gap by giving them access to the facilities and expertise required to test whether their innovations remain technically and economically viable at larger scale.

For SMEs approaching commercialisation, this can provide important evidence for future customers, manufacturing partners, regulators and investors.

How Inventya Can Help

Applications to this competition need to demonstrate much more than scientific novelty. They must show that the technology is genuinely ready for scale-up, that the right infrastructure partner is involved and that the project can create a credible route towards commercial deployment.

Inventya can support applicants with:

  • Eligibility and project scoping: assessing whether the technology, maturity level, proposed activities and project structure fit the competition.
  • Partner and infrastructure strategy: helping define the capabilities required from a scale-up partner and building a clear rationale for their involvement.
  • Technical and commercial narrative: connecting the laboratory evidence, scale-up challenge, validation plan and commercial opportunity into one coherent case.
  • Market and route-to-market development: strengthening the customer need, target market, competitive position and commercialisation strategy.
  • Project planning and risk management: developing work packages, milestones, scale-up activities, risks and mitigation measures.
  • Full application development: preparing clear and evidence-based responses across innovation, market, impact, project delivery, added value and value for money sections.

Inventya can help ensure the application presents the project not simply as a technical scale-up exercise, but as a clear pathway from lab-proven engineering biology innovation to a commercially viable and scalable UK opportunity.

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